| 28th June 2013 |
Established with the capital of 20,000,000 yen |
| 24th July 2013 |
Applied Patent 1: Therapeutic drug and therapeutic method for neurological diseases including Alzheimer’s disease associated with 1,25 D3-MARRS |
| 21st Apr 2015 |
Applied Patent 2: Therapeutic agent for diseases associated with nerve axon dysfunction, including therapeutic agent for Alzheimer’s disease |
| 30th June 2015 |
As a division of Patent 1: Resilio applied for patent 3 that Diosgenin, 1,25 D3-MARRS etc., has effect on various neurological diseases through food and drink supplements and additives |
| 7th Aug 2015 |
Registered Patent 1, Registration Number : 5789339 |
| Jan 2016 |
Commence the double-blind crossover clinical trial of Diosgenin |
| 8th June 2016 |
The capital increased to 27,000,000 yen through increase in shareholder allocation |
| 18th Aug 2016 |
Applied Patent 4: ActivatIng agent for reconstitution of the neural network |
| Nov 2016 |
Completion of the clinical trial |
| Feb 2017 |
Completion of analysis with the clinical trial results |
| 30th June 2017 |
Registered Patent 2, Registration Number : 6165323 |
| 30th June 2017 |
Registered Patent 4, Registration Number : 6165380 |
| 29th Sep 2017 |
The capital increased to 39,600,000 yen through increase in third-party allocation. |
| 5th Jan 2018 |
Registered Patent 3, Registration Number : 6267160 |
| 18th Jan 2018 |
Received the patent objection(2018-700039) against the Patent 2, Already submitted the reasoned comments |
| 18th Apr 2018 |
The office established at the current address |
| April 2018 |
Clinical research summary with Diosgenin in Yam contributed at the monthly journal ”Gekkan Kenko vol.April” published by Shufunotomo-sha |
| Aug 2018 |
The article titled“ The Secret of Prevention and Treatment for Dementia” based on the clinical research with Diosgenin in Yam, contributed at the monthly journal ”Soukai vol.August” published by Makino-Shuppan |
| Oct 2018 |
The article titled“ Series of Dementia, Look at this Person” based on the clinical research with Diosgenin in Yam, contributed at the monthly journal ”Kenko 365 vol.October 2018” published by H&I inc |
| Nov 2018 |
Our supplement ”Diosgenin Gold” started marketing in Japan. |
| Jul 2019 |
Solved the patent objection issue(2018-700039) against the Patent 2, Maintenance of the Patent 2(6165323) decided |
